Medicine & Surgery
Subbarow: ATP, folic acid and methotrexate
1920s-1948Yellapragada SubbarowHarvard and Lederle Laboratories researchDiaspora (work abroad)
1920
Co-discovered phosphocreatine and ATP's role in muscle, synthesised folic acid and led work yielding methotrexate and aureomycin.
- Dated
- 1920–1948
- As scholars put it
- 1920s-1948
- Originator
- Yellapragada Subbarow
- Source text
- Harvard and Lederle Laboratories research
- Region
- Diaspora (work abroad)
- Discipline
- Medicine & Surgery
- Evidence
- Documented
- Confidence
- High
- Verification
- Reference-cited
Meanwhile in the West
Credit often went to colleagues.
Fair to say
By an India-born scientist working in the US; under-recognised in his lifetime.
Path to modern innovation
Methotrexate remains a key cancer and arthritis drug.
Transmission
Work done in the US (diaspora).
References
- 1Fiske & Subbarow (1925)
- 2Lederle records
Further reading
Corrections and additional sources: edit IND-285 on GitHub.